What happened
The Scottish Government asked the Scottish Health Technologies Group (SHTG) whether NICE's guidance on HeartFlow FFRCT should apply in NHSScotland. SHTG put three rounds of questions to Scottish experts and published its adapted advice on 13 September 2021. It advised that FFRCT is non-invasive and safe and may improve diagnosis by raising specificity after CT coronary angiography. It added that FFRCT may reduce the need for invasive coronary angiography and could lead to cost savings. Its council judged the supporting evidence to be of limited quality, citing non-randomized and post hoc studies. The council saw particular value in remote areas, where patients would otherwise travel far for tests. NHS Western Isles had begun a 40-scan pilot in December 2020. SHTG found the size of any savings uncertain because clinical practice varies. It describes FFRCT as simulation software and does not say that it learns from data.
Sources
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Assessment report, by authors with no tie to the system.
Scottish Health Technologies Group, Healthcare Improvement Scotland. HeartFlow FFRCT for estimating fractional flow reserve from coronary CT angiography: Recommendation for NHSScotland (SHTG Adaptation of NICE guidance). Published 13 September 2021. Archived copy of 27 April 2025.
Compared with standard care, using HeartFlow FFRCT may reduce the requirement for invasive coronary angiography (ICA) to further assess patients with CAD, though noting that the quality of supporting clinical-effectiveness evidence was limited.
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Assessment report, by authors with no tie to the system.
Scottish Health Technologies Group. SHTG Adaptation: HeartFlow FFRCT for estimating fractional flow reserve from coronary CT angiography. 3 September 2021, Scottish Health Technology Council considerations.
The Council noted that ICA carries a risk of adverse events, and recognised the potential opportunity for HeartFlow FFRCT to reduce the need for invasive procedures.
Details
AI system
- Workflow
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HeartFlow FFRCT used data from an existing CT coronary angiography scan, so patients did not need to attend for the test. Clinicians used FFRCT alongside other diagnostic tools to decide who needed invasive angiography.
Follow-up
- Conditions for replication
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Scans come from a 64-slice or better CT scanner with adequate image quality. Health boards have access to CT coronary angiography, which varied across Scotland.
Entry details
- Sector
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Healthcare.
- Purpose
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HeartFlow built HeartFlow FFRCT to calculate fractional flow reserve from coronary CT angiography, so that clinicians can judge which narrowed arteries limit blood flow without an invasive test.
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Cite this record
Peter H. Vartanian. (2026). Scotland backs HeartFlow FFRCT as an option to avoid invasive tests (AIBD-1123). Artificial Intelligence Benefits Database, edition of 1 November 2026. https://petervartanian.xyz/aibd/records/AIBD-1123.html (archived at https://doi.org/10.7910/DVN/AADSII, version 7.0)