Pregnant women gain knowledge and receive more recommended care

Women invited to PROMPTS improved several measures of knowledge, preparation for childbirth, and reported care by 0.06–0.09 standard deviations.

AI system

System

PROMPTS. [1]

Model

An earlier Google Cloud classifier preceded TRIM-AI. The later system adapted XLM-RoBERTa-large as XLM-RoBERTa-JH. [2]

Release

The exact deployment release and each trial participant’s exposure to it are not reported. [1] [2]

Editor’s note. The trial ran from November 2021 through August 2022, while the technical paper dates TRIM-AI deployment to June 2022. Its use during the latter part of follow-up is plausible, but the trial does not report participants’ exposure by model.

Provider

Jacaranda Health. [1]

Role

Natural language processing classified messages for routine replies or clinical helpdesk review. [1]

Configuration

The later TRIM-AI classifier adapted a multilingual model using 939,819 messages, then trained for 58 intents on 107,714 labeled messages. [2]

Inputs and outputs

Women sent questions by SMS. The platform classified their intent and urgency, then provided guidance or routed the message to clinicians. [1]

Autonomy

In the documented TRIM-AI workflow, sufficiently confident classifications triggered vetted replies. Failed or uncertain exchanges went to staff. [2]

Workflow

Women received scheduled messages and reminders and could text the helpdesk. Clinicians handled questions that required human review. [1]

Human oversight

Clinical staff prepared responses and handled escalated messages. The technical evaluation asked users whether automated answers were helpful. [2]

Relation to AI

The helpdesk used natural language processing to sort incoming questions. [1]

AI contribution

The trial evaluated the complete platform. It did not measure the separate effect of the NLP helpdesk. [1]

Benefits

Outcome identifiers

Not assessed

Benefit

The invitation to use PROMPTS improved several measures of knowledge, preparation, and care. [1]

Category

Improved health knowledge and use of recommended maternal and newborn care. [1]

Status

Observed in a randomized evaluation. [1]

Beneficiary groups

Pregnant and postpartum women and their newborns. [1]

Beneficiaries

Women attending participating facilities who had access to a mobile phone. [1]

Reach

The trial enrolled 6,139 women: 3,140 at treatment facilities and 2,999 at control facilities. [1]

Distribution and access

The trial covered public and faith-based facilities in eight counties. It excluded women without phone access. [1]

Duration

Researchers followed participants from pregnancy into the early postpartum period. [1]

Expected?

Better knowledge and care were the intended benefits. [1]

Costs and harms

The service depended on phone access and did not replace clinical care. The trial did not establish effects on deaths or serious illness. [1]

Measurement

Studies

AIBD-0100-E01, AIBD-0100-E02 [1] [2]

Study design

Twenty facilities introduced PROMPTS and twenty continued usual care. Assignment was stratified within counties. [1]

Measurement

Telephone surveys measured knowledge and reported care. Analysis compared assigned groups and accounted for clustering by facility. [1]

Setting and sample

There were 6,139 participants at 40 facilities. Researchers completed 5,509 of 6,128 eligible postpartum interviews. [1]

Measures

Knowledge, birth preparation, routine and danger-sign care, newborn care, and postpartum care content. [1]

Comparison

Women at control facilities were not systematically introduced to PROMPTS, although they could join independently. [1]

Results

Five indices improved by 0.06–0.09 standard deviations. Care-seeking for danger signs did not differ significantly. [1]

Additional value from AI

The evaluation did not separate automated triage from information, reminders, or clinician support. [1]

Limitations

Outcomes were self-reported. The study was not powered for clinical outcomes, and a parallel nurse-training program could have influenced care. [1]

Denominators

Among treatment participants surveyed during pregnancy, 1,453 of 1,700 reported joining PROMPTS. [1]

Materials for replication

The public repository contains analysis code and documentation. Participant data remain restricted under the study’s approvals. [1]

Money

Kind of value

A provider estimate of enrollment cost and a separate estimate of NLP operating costs. [2] [3]

Amount

Jacaranda estimated US$0.74 per enrollee over their time on PROMPTS. The technical paper reports monthly NLP costs falling from US$819 to US$632. [2] [3]

Currency and prices

The sources report U.S. dollars. The technical paper also gives about KES 24,000 for its rounded monthly saving of about US$200. [2] [3]

Period and unit

Per enrollee over their time on the platform, and per month for the separate NLP estimate. [2] [3]

Realization

Both figures are provider estimates. The trial did not audit them or measure a net monetary benefit. [2] [3]

Recipients and payers

Jacaranda and its partners fund delivery. Participants use PROMPTS free of charge. [2] [3]

Gross or net

The enrollment figure is a cost. The technical saving covers model and translation services, not the full health program. [2] [3]

Included costs

The enrollment estimate covers messages, technical infrastructure, enrollment work, and county partnerships. [2] [3]

Comparison

The technical comparison is the earlier Google Cloud classifier plus translation versus TRIM-AI. [2] [3]

Method

Jacaranda supplied the operating estimates. Subtracting US$632 from US$819 gives US$187 per month. [2] [3]

Return and payback

No full financial return or payback period is reported. [1] [2] [3]

People and places

Participants

Jacaranda Health ran PROMPTS with Kenyan health facilities. Academic researchers and Innovations for Poverty Action evaluated it with the provider. [1]

Jurisdictions

Forty facilities participated across Kajiado, Kilifi, Kirinyaga, Kisii, Meru, Narok, Nyeri, and Siaya counties in Kenya. [1]

Ownership and control

Jacaranda Health operated the platform. Participating facilities helped enroll women. [1]

Dependencies

Women needed access to a phone that could receive texts. The service also needed mobile networks, facility enrollment, and clinical helpdesk staff. [1]

Cross-border connections

The technical work involved Kenyan and U.S. institutions and Google Cloud services. The papers do not establish where participants’ messages were stored. [1] [2]

Geopolitical implications

Not assessed

Follow-up

Conditions for replication

Women need access to SMS, facilities must support enrollment, and clinicians must be available for escalated questions. [1]

Replication attempts

The later report documents expansion, rather than a new randomized test of the Kenyan trial result. [4]

Later findings

For July–September 2025, Jacaranda reported cumulative reach of 3,580,095 mothers across 23 Kenyan counties and 1,500 facilities. [4]

Availability

Jacaranda reported continued operation in Kenya and an agreement for national expansion in Ghana during 2025. [4]

Institutional decision

Not assessed

Grounds

Not assessed

Action and result

Not assessed

Success criterion

Not assessed

Evidence

Source numbers

AIBD-0100-source-0001, AIBD-0100-source-0002, AIBD-0100-source-0003, AIBD-0100-source-0004 [1] [2] [3] [4]

Citations

The trial provides the benefit findings. Its references lead to the original NLP paper and provider cost estimate. A later provider report covers expansion. [1] [2] [3] [4]

Language

English. [1] [2] [3] [4]

Source relationships

The benefit study includes both outside researchers and Jacaranda. The technical and cost claims come from the developer partnership and provider. [1] [2] [3] [4]

Original evidence

The trial cites the technical paper for NLP and the provider’s brochure for costs. Those original sources are retained. [1] [2] [3] [4]

Access and versions

Original papers, relevant supplements, technical appendix, and provider reports were inspected. Model exposure by trial participant remains unresolved. [1] [2] [3] [4]

Supported findings

Offering the complete platform improved several reported measures of knowledge and care. [1]

Evidence strength

A peer-reviewed cluster randomized trial supports the platform’s effects. The evaluation included the provider and outside researchers. [1]

Missing evidence

Not assessed

Grades

Assessed benefits

Women’s health knowledge and reported care practices. [1]

Depth

Personal: 2 [1]

Reasons

Women had measurable improvements in knowledge and reported care practices. [1]

Observed or intended

Observed in a randomized evaluation. [1]

Rubric

Not assessed

Assessor and date

Not assessed

Alternative assessments

Not assessed

Fill

The deployer's account [1] [2] [3] [4]

Entry details

Kind

A trial that randomized health facilities to introduce a digital health platform. [1]

Field

Maternal and newborn health. [1]

Purpose

PROMPTS provided pregnancy information, reminders, and help with questions through text messages. [1]

Dates

Recruitment ran from 8 November to 10 December 2021. Follow-up continued through 24 August 2022. [1]

Stage

The platform was operating in Kenya when the trial began. [1]

Version

SHA-256: aa41a37d6114…

References

Other identifiers

AI Incident Database: 545.

Category mappings

Not assessed

Brief

Not assessed

Revisions

8 revisions. Latest: 25 October 2026.

Sources

  1. Peer-reviewed study Evaluator

    Vatsa, Rajet, et al. PLOS Medicine 22, no. 2 (2025): e1004527. https://doi.org/10.1371/journal.pmed.1004527.

    Original trial of the complete platform, with sample, methods, outcomes, and limitations. Methods, Tables 1–6, discussion, and S1–S2 Text.

    Primary study by researchers from Harvard, the World Bank, Innovations for Poverty Action, and Jacaranda Health. Five authors were Jacaranda employees.

    Access copy, supplement, or earlier version of the same work. Published article. Published article.

    Access copy, supplement, or earlier version of the same work.

    Access copy, supplement, or earlier version of the same work. S1 Text, randomization. S1 Text, randomization.

    Access copy, supplement, or earlier version of the same work.

    Access copy, supplement, or earlier version of the same work. S2 Text, outcomes omitted or changed from preregistration. S2 Text, outcomes omitted or changed from preregistration.

    Access copy, supplement, or earlier version of the same work.

  2. Peer-reviewed study Developer

    Zhang, Wenbo, et al. Proceedings of the AAAI Conference on Artificial Intelligence 37, no. 12 (2023): 14620–27. https://doi.org/10.1609/aaai.v37i12.26709.

    Original technical account of the earlier classifier, TRIM-AI, deployment date, response workflow, and estimated operating costs. pp. 14621–26 and online appendix.

    Primary technical study by the developers and Jacaranda Health.

    Access copy, supplement, or earlier version of the same work. Published technical paper. Published technical paper.

    Access copy, supplement, or earlier version of the same work.

    Access copy, supplement, or earlier version of the same work. Original online appendix. Original online appendix.

    Access copy, supplement, or earlier version of the same work.

  3. Report Deployer

    Jacaranda Health. PROMPTS. Program brochure, n.d.

    Original provider estimate of lifetime cost per enrollee and description of the clinical helpdesk. p. 2, costs; p. 3, helpdesk and AI.

    Provider’s own operational account. This is the source that R1 cites for cost and some platform details.

  4. Report Deployer

    Jacaranda Health. Q3 Impact Report: July–September 2025.

    Later cumulative enrollment and service expansion, distinct from the trial’s measured effects. Opening scale figures and Ghana expansion section.

    Original provider report. Enrollment totals are reach, not counts of people with a measured benefit.