Neuromotus EMG decoding restores thumb and wrist movement

A 72-year-old with a paralyzed replanted arm regained active thumb and wrist movement after 18 sessions of ML-decoded motor execution.

21ⓘ

AI system

System

Myoelectric motor execution with sensory training: Neuromotus 8-channel EMG and LDA classifier driving virtual limbs and serious games

Model

A classifier based on linear discriminant analysis.

Release

Exact release not established.

Application developer

Center for Bionics and Pain Research / University of Gothenburg (academic clinical team); device by Integrum AB

Role

The classifier decoded intended movements from muscle signals and controlled a virtual limb.

Configuration

The Neuromotus system used a classifier based on linear discriminant analysis.

Inputs and outputs

Not assessed

Autonomy

Not assessed

Workflow

Residual EMG detectable in the impaired limb. Classifier trained on the patient's own signals each session. Repeated sessions with virtual-limb and game feedback.

Human oversight

Not assessed

Relation to AI

The LDA classifier decodes intended movements from weak EMG in a hand and wrist with no active motion. That is the only way the patient could receive real-time feedback on his motor attempts. The authors attribute the regained movement to this motor execution training. Two authors hold a pending patent on the technology.

AI contribution

The LDA classifier decodes intended movements from weak EMG in a hand and wrist with no active motion. That is the only way the patient could receive real-time feedback on his motor attempts. The authors attribute the regained movement to this motor execution training. Two authors hold a pending patent on the technology.

Benefits

Outcome identifiers

Not assessed

Benefit

active thumb extension (4 degrees) and active wrist flexion (6 degrees)

Category

Improved Physical Health

Status

Not assessed

Beneficiary groups

People. Society.

Beneficiaries

Not assessed

Reach

Not assessed

Distribution and access

Not assessed

Duration

Not assessed

Expected?

Yes

Costs and harms

Not assessed

Measurement

Studies

Not assessed

Study design

Not assessed

Measurement

Not assessed

Setting and sample

Not assessed

Measures

active thumb extension (4 degrees) and active wrist flexion (6 degrees)

Comparison

the arm's function before treatment, after conventional rehabilitation

Results

Reference: no active movement prior the MME interventions. Result: active extension of the thumb (4 degrees) and regained active wrist movement (flex: 6 degrees, extend: 10 degrees).

Additional value from AI

Not assessed

Limitations

Not assessed

Denominators

Not assessed

Materials for replication

Not assessed

Money

Kind of value

Not assessed

Amount

Not assessed

Currency and prices

Not assessed

Period and unit

Not assessed

Realization

Not assessed

Recipients and payers

Not assessed

Gross or net

Not assessed

Included costs

Not assessed

Comparison

Not assessed

Method

Not assessed

Return and payback

Not assessed

People and places

Participants

Developer: Center for Bionics and Pain Research / University of Gothenburg (academic clinical team); device by Integrum AB. Operator: Center for Bionics and Pain Research and Sahlgrenska University Hospital (C.A.R.E.), Mölndal; treatment site not named in the paper.

Jurisdictions

Benefit: Mölndal, Sweden. Developer: Sweden. Operator: Sweden.

Ownership and control

Not assessed

Dependencies

Not assessed

Cross-border connections

Not assessed

Geopolitical implications

Not assessed

Follow-up

Conditions for replication

Intact or reinnervated muscle producing separable EMG patterns. Clinician-run sessions several times a week. Patient motivation to attempt movements without visible motion.

Replication attempts

1 follow-up entries. Benefit recurred: 1.

Later findings

No follow-up beyond the final session is reported.

Availability

Not assessed

Institutional decision

Not assessed

Grounds

Not assessed

Action and result

Not assessed

Success criterion

Not assessed

Evidence

Source numbers

AIBD-0055-source-0001–0003

Citations

Numbered references below.

Language

Not assessed

Source relationships

Developer

Original evidence

Not assessed

Access and versions

Not assessed

Supported findings

Not assessed

Evidence strength

Not assessed

Missing evidence

Not assessed

Grades

Assessed benefits

People. Society.

Depth

People: 2. Society: 1.

Reasons

People: An identifiable patient regained active thumb and wrist movement conventional rehabilitation had not produced. Gains are small and pain did not consistently improve. Society: Single case; authors present it as a potential treatment needing further study.

Observed or intended

Not assessed

Rubric

Not assessed

Assessor and date

Not assessed

Alternative assessments

Not assessed

Fill

The makers' claim

Entry details

Kind

Not assessed

Field

Rehabilitation medicine / hand surgery. Patients with replanted or transplanted limbs.

Purpose

Rehabilitate a highly impaired replanted arm and reduce neuropathic pain using decoded motor intention as feedback

Dates

Date basis unassessed: 2024 (precision unassessed). Updated: 21 October 2026.

Stage

Not assessed

Version

SHA-256: 8f82e8810e83…

References

Other identifiers

Not assessed

Category mappings

Not assessed

Brief

Not assessed

Revisions

6 revisions. Latest: 21 October 2026.

Sources

  1. Peer-reviewed study Developer

    Munoz-Novoa M, Kristoffersen MB, Sunnerhagen KS, Naber A, Ortiz-Catalan M, Alt Murphy M (2025). Myoelectric pattern recognition with virtual reality and serious gaming improves upper limb function in chronic stroke: a single case experimental design study. Journal of NeuroEngineering and Rehabilitation 22:6.

  2. Case report Developer

    Kristoffersen MB, Munoz-Novoa M, Buist M, Emadeldin M, Reinholdt C, Ortiz-Catalan M (2024). Myoelectric motor execution and sensory training to treat chronic pain and paralysis in a replanted arm: a case study. Journal of NeuroEngineering and Rehabilitation 21:204.