What happened
The Veterans Health Administration (VHA) built STORM, the Stratification Tool for Opioid Risk Mitigation. Its dashboard uses predictive analytics to stratify patients prescribed opioids by risk of an overdose- or suicide-related event. In March 2018, VHA required interdisciplinary case reviews for patients whom STORM rated very high risk. Medical centers were randomized to raise that cutoff from the top 1% to the top 5% of risk in February or August 2019. VA researchers analyzed 44,042 patients in all 140 medical centers and published the results on 2 May 2022. Patients under the mandate were five times more likely to receive a case review. They had 22% lower odds of death within four months (odds ratio 0.78, 95% confidence interval 0.65 to 0.94). The authors detected no effect on the nine serious adverse events that were the primary outcomes. Mortality was an exploratory outcome added after the trial began. Unadjusted death rates were 6.7% without the mandate and 6.9% with it. The 22% figure comes from a model that adjusts for month, facility and patient characteristics.
Sources
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Peer-reviewed study, by the organization that used it.
Strombotne KL, Legler A, Minegishi T, Trafton JA, Oliva EM, Lewis ET, Sohoni P, Garrido MM, Pizer SD, Frakt AB. Effect of a Predictive Analytics-Targeted Program in Patients on Opioids: a Stepped-Wedge Cluster Randomized Controlled Trial. Journal of General Internal Medicine 38(2):375-381, published online 2 May 2022 (PMC9060407). The authors work at VA's Partnered Evidence-based Policy Resource Center and at the Program Evaluation and Resource Center of VHA's Office of Mental Health and Suicide Prevention, and VHA funded the work.
Mandated review inclusion was associated with a significant decrease in all-cause mortality within 4 months of inclusion (OR: 0.78; 95% CI: 0.65-0.94).
Details
AI system
- Workflow
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STORM computed each patient's risk of an overdose- or suicide-related event in the next year from VHA records. VHA Notice 2018-08 required interdisciplinary teams to review every patient whom STORM rated very high risk. Each review covered the patient's risks, prescriptions and risk mitigation strategies and was documented in the medical record.
Follow-up
- Conditions for replication
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The patient is prescribed opioid analgesics and has a predicted risk between the top 1% and 5% nationally. Clinicians have the time to complete case reviews for an expanded high-risk cohort. The risk scores keep their performance over time and across populations.
Entry details
- Sector
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Healthcare (opioid safety).
- Purpose
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The Veterans Health Administration built STORM to stratify patients prescribed opioids by their risk of an overdose- or suicide-related event and to support decisions on lowering that risk.
References
- Other identifiers
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Isrctn: ISRCTN16012111.
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Cite this record
Peter H. Vartanian. (2026). Veterans flagged by STORM for case review die less often in a VA trial (AIBD-1008). Artificial Intelligence Benefits Database, edition of 1 November 2026. https://petervartanian.xyz/aibd/records/AIBD-1008.html (archived at https://doi.org/10.7910/DVN/AADSII, version 7.0)