What happened
Vertebral fragility fractures are the most common fractures caused by osteoporosis, and clinical experts told NICE that most remain undiagnosed. AI tools can check CT scans taken for other reasons and flag such fractures. The National Institute for Health and Care Excellence (NICE) assessed eight tools in an early value assessment published on 14 October 2025. Its assessors found 22 studies, most of them retrospective, and three more arrived during consultation. Thirteen studies compared the tools with standard care, mostly the original radiology report, and most were done outside the UK. The committee concluded that the tools can detect additional moderate to severe fractures that the original reports missed, generally with a specificity above 90%. It was uncertain how much detection would improve in the NHS. NICE allowed BriefCase-Triage, CINA-VCF Quantix, HealthVCF, HealthOST and IB Lab FLAMINGO during a three-year evidence generation period. The algorithms are fixed and work in addition to standard radiology review. More flagged fractures could add radiology work and bone density scans.
Sources
-
Assessment report, by authors with no tie to the system.
The committee concluded that, overall, the evidence suggests that the AI technologies can detect additional moderate to severe vertebral fractures (as confirmed by a reference standard) that were not reported in the original radiology report. Generally, the technologies could detect these fractures with a specificity above 90%.
-
Assessment report, by authors with no tie to the system.
Five artificial intelligence (AI) technologies can be used in the NHS during the evidence generation period as options to aid the opportunistic detection of vertebral fragility fractures (VFFs).
Details
AI system
- Workflow
-
The tools analyzed chest and abdominal CT scans taken for other reasons. Radiologists still reviewed every scan in the usual way.
Follow-up
- Conditions for replication
-
Local protocols refer people with a newly found fracture for assessment and treatment. Radiology and bone density scanning services can absorb the extra referrals.
Entry details
- Sector
-
Healthcare (radiology and osteoporosis).
- Purpose
-
Aidoc Medical, Avicenna.AI, Nanox AI and IB Lab built their tools to flag vertebral fractures on CT scans taken for other reasons.
Not yet checked: model, release, provider, role, configuration, inputs and outputs, autonomy, human oversight, beneficiaries, reach, distribution and access, duration, every measurement question, every money question, ownership and control, dependencies, cross-border connections, geopolitical implications, replication attempts, availability, institutional decision, grounds, action and result, success criterion, every evidence question, observed or intended, alternative assessments, related entries, other identifiers, category mappings.
Cite this record
Peter H. Vartanian. (2026). AI tools spot spinal fractures missed in routine scan reports (AIBD-0739). Artificial Intelligence Benefits Database, edition of 31 October 2026. https://petervartanian.xyz/aibd/records/AIBD-0739.html (archived at https://doi.org/10.7910/DVN/AADSII, version 4.0)