Nelli flags 247 nocturnal seizure events missed by carers

Cornwall NHS evaluation (15 people who could not tolerate EEG): Nelli flagged 707 possible seizure events, 247 unheard or unrecognised by carers; Danish phase-3 validation sensitivity 93.7%.

AI system

System

Nelli audio-video seizure monitoring system (computer vision and AI-based event detection)

Model

Not assessed

Release

Not assessed

Application developer

Neuro Event Labs, Tampere, Finland

Role

Not assessed

Configuration

Not assessed

Inputs and outputs

Not assessed

Autonomy

Not assessed

Workflow

A camera and microphone unit streaming to a server where computer-vision and AI algorithms flag motor events. Night-time use for people with suspected nocturnal seizures who could not tolerate EEG, with family or carer consent. Clinician review of flagged clips (the Cornwall paper says 8–9% of the recording is sampled by an epilepsy expert).

Human oversight

Not assessed

Relation to AI

The system flagged motor events that night staff and carers had not noticed (247 of 707 in Cornwall). In the Danish validation it detected every tonic-clonic seizure in real time. Clinicians still reviewed sampled clips to confirm events. Sensitivity for minor motor seizures was 8.3%. One Cornwall participant's unit was removed to prevent injury and equipment damage. The validation paper is co-authored by two vendor employees. The Cornwall evaluation is independent of the maker.

AI contribution

The system flagged motor events that night staff and carers had not noticed (247 of 707 in Cornwall). In the Danish validation it detected every tonic-clonic seizure in real time. Clinicians still reviewed sampled clips to confirm events. Sensitivity for minor motor seizures was 8.3%. One Cornwall participant's unit was removed to prevent injury and equipment damage. The validation paper is co-authored by two vendor employees. The Cornwall evaluation is independent of the maker.

Benefits

Outcome identifiers

Not assessed

Benefit

Nelli flagged 707 possible seizure events, 247 unheard or unrecognised by carers

Category

Improved Physical Health

Status

Not assessed

Beneficiary groups

People. Organizations.

Beneficiaries

Not assessed

Reach

Not assessed

Distribution and access

Not assessed

Duration

Not assessed

Expected?

Yes

Costs and harms

Not assessed

Measurement

Studies

Not assessed

Study design

Not assessed

Measurement

Not assessed

Setting and sample

Not assessed

Measures

Nelli flagged 707 possible seizure events, 247 unheard or unrecognised by carers

Comparison

carers' hearing or recognition of night-time events in the same people

Results

Reference: 247 were not heard or recognised by carers. Result: Nelli recorded 707 possible seizure events across the study cohort.

Additional value from AI

Not assessed

Limitations

Not assessed

Denominators

Not assessed

Materials for replication

Not assessed

Money

Kind of value

Not assessed

Amount

Not assessed

Currency and prices

Not assessed

Period and unit

Not assessed

Realization

Not assessed

Recipients and payers

Not assessed

Gross or net

Not assessed

Included costs

Not assessed

Comparison

Not assessed

Method

Not assessed

Return and payback

Not assessed

People and places

Participants

Developer: Neuro Event Labs, Tampere, Finland. Operator: Cornwall Partnership NHS Foundation Trust (community evaluation); Danish Epilepsy Center, Dianalund, and Aarhus University Hospital (validation).

Jurisdictions

Benefit: Cornwall, United Kingdom; Dianalund and Aarhus, Denmark. Developer: Finland. Operator: United Kingdom.

Ownership and control

Not assessed

Dependencies

Not assessed

Cross-border connections

Not assessed

Geopolitical implications

Not assessed

Follow-up

Conditions for replication

Device deficiency kept low (10.5% of monitored time in the Danish validation). Staff available at night to act on alarms, the setting the validators say the system is suited to. The target is major motor seizures; minor motor seizures were detected at 8.3% sensitivity.

Replication attempts

1 follow-up entries. Benefit recurred: 1.

Later findings

9 October 2025. A later single-center feasibility study in Dravet and Lennox-Gastaut syndromes, with vendor co-authors, reported that Nelli detected 368 seizures at 97.8% accuracy over four weeks of home monitoring while diaries documented only 26.1% of seizures.

Availability

Not assessed

Institutional decision

Not assessed

Grounds

Not assessed

Action and result

Not assessed

Success criterion

Not assessed

Evidence

Source numbers

AIBD-0297-source-0001–0005

Citations

Numbered references below.

Language

Not assessed

Source relationships

Operator, Developer

Original evidence

Not assessed

Access and versions

Not assessed

Supported findings

Not assessed

Evidence strength

Not assessed

Missing evidence

Not assessed

Grades

Assessed benefits

People. Organizations.

Depth

Not assessed

Reasons

People: Carers reported peace of mind (13 of 14). Clinicians gained event counts for people who cannot report seizures. No cited source documents a treatment change or injury avoided for a named individual. Organizations: The Cornwall authors describe improved care planning and carer training. No measured change in staffing, response times or incidents is reported.

Observed or intended

Not assessed

Rubric

Not assessed

Assessor and date

Not assessed

Alternative assessments

Not assessed

Fill

The deployer's account

Entry details

Kind

Not assessed

Field

Healthcare (epilepsy; nocturnal seizure monitoring). Residential and institutional seizure monitoring for people with intellectual disability.

Purpose

Built to detect nocturnal major motor seizures from audio-video so that staff can intervene and clinicians can see events patients cannot report. The unrecognized events it surfaced are that purpose.

Dates

Date basis unassessed: 2023 (precision unassessed). Updated: 21 October 2026.

Stage

Not assessed

Version

SHA-256: 916bef6a0a2a…

References

Other identifiers

Not assessed

Category mappings

Not assessed

Brief

Not assessed

Revisions

5 revisions. Latest: 21 October 2026.

Sources

  1. Peer-reviewed study Deployer

    Lennard S, Newman R, McLean B, Jory C, Cox D, Young C, Corson E, Shankar R (2023). Improving nocturnal event monitoring in people with intellectual disability in community using an artificial intelligence camera. Epilepsy & Behavior Reports 22:100603 (PMC10160340).

  2. Peer-reviewed study Developer

    Armand Larsen S, Terney D, Østerkjerhuus T, Vinding Merinder T, Annala K, Knight A, Beniczky S (2022). Automated detection of nocturnal motor seizures using an audio-video system. Brain and Behavior 12(9):e2737 (PMC9480955). Annala and Knight are Neuro Event Labs employees and shareholders.

  3. Peer-reviewed study Developer

    Wilms LK, Lossius MI, Annala K, Abdel-Khalik J, Fanter L, Elomaa K, Peltola J (2025). Seizure classification using a multimodal seizure monitoring system (Nelli) in Dravet and Lennox-Gastaut syndromes: A non-randomized, single-center feasibility study. Epilepsia, online 9 October 2025; doi:10.1111/epi.18640 (PMID 41066202; PMC12893256). Neuro Event Labs co-authors.