Turkish Brain Project algorithm flags a glioma mid-scan at Gazi

Real-time MRI algorithm at Gazi University Hospital alerted doctors to a 46-year-old woman's glioma mid-scan; biopsy next day, Oct 2022.

AI system

System

Turkish Brain Project real-time brain MRI alert system at Gazi University: a region-based convolutional neural network object-detection algorithm integrated into the hospital network, which processes MRI images in real time; Anadolu Agency reports that it evaluates a brain MRI within 5-10 seconds while the patient is still in the scanner and sends the physicians' mobile phones a message with the abnormal regions segmented, through a GSM operator's picture-message service

Model

Not assessed

Release

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Application developer

Gazi University, Ankara (Department of Neurosurgery and Department of Computer Engineering), within the Turkish Brain Project funded by the Presidency of the Republic of Türkiye, with the Presidency's Digital Transformation Office credited for the model's development

Role

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Configuration

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Inputs and outputs

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Autonomy

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Workflow

A region-based convolutional neural network object-detection algorithm trained on a brain MRI data set built within the Turkish Brain Project. Anadolu Agency: six months of training on stroke, hemorrhage and tumor cases. Integration into the hospital network so MRI images are processed as they are acquired. Anadolu Agency reports evaluation within 5–10 seconds on the hospital's three MRI scanners. An alert channel to the physicians' mobile phones, reported by Anadolu Agency as a GSM operator's picture-message service carrying the segmented abnormal regions. A neurosurgery team that reads the alert at once and can admit and biopsy the patient within a day.

Human oversight

Physicians reviewed the images and admitted the patient. A biopsy and pathology examination established the diagnosis.

Relation to AI

The algorithm detected the mass on the real-time MRI data and raised the alert while the patient was still in the scanner. Physicians then read the images, judged the finding consistent with a diffuse glioma and admitted her. The diagnosis itself came from the pathology report after the stereotactic biopsy. What the AI contributed is detection and speed, not a different diagnosis or treatment. The counterfactual is unproven. The authors say radiology would typically take days to report and that further investigations are needed on the advantages of earlier treatment. They give no evidence of what delay this patient would otherwise have faced. The case is reported by the team that built and deployed the algorithm, and the Anadolu Agency coverage carries that team's account. No independent clinical review is cited.

AI contribution

The Turkish Brain Project system detected a mass and alerted physicians while the patient was still undergoing an MRI scan.

Benefits

Outcome identifiers

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Benefit

Real-time MRI algorithm at Gazi University Hospital alerted doctors to a 46-year-old woman's glioma mid-scan; biopsy next day, Oct 2022.

Category

Improved Physical Health

Status

Not assessed

Beneficiary groups

People.

Beneficiaries

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Reach

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Distribution and access

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Duration

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Expected?

Yes

Costs and harms

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Measurement

Studies

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Study design

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Measurement

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Setting and sample

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Measures

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Comparison

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Results

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Additional value from AI

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Limitations

The developers reported the case. They did not measure how long this patient would otherwise have waited or whether earlier treatment improved her outcome. The cited news coverage repeats the team’s account.

Denominators

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Materials for replication

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Money

Kind of value

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Amount

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Currency and prices

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Period and unit

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Realization

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Recipients and payers

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Gross or net

Not assessed

Included costs

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Comparison

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Method

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Return and payback

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People and places

Participants

Developer: Gazi University, Ankara (Department of Neurosurgery and Department of Computer Engineering), within the Turkish Brain Project funded by the Presidency of the Republic of Türkiye, with the Presidency's Digital Transformation Office credited for the model's development. Operator: Gazi University, Department of Neurosurgery, Ankara.

Jurisdictions

Benefit: Ankara, Turkey. Developer: Turkey. Operator: Turkey.

Ownership and control

Not assessed

Dependencies

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Cross-border connections

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Geopolitical implications

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Follow-up

Conditions for replication

The lesion is of a kind the model was trained on (the team names stroke, hemorrhage and tumor). The alert reaches a physician who acts on it before the routine radiology report. The hospital can schedule a biopsy or operation promptly. False alerts stay low enough that physicians keep trusting the messages. Anadolu Agency quotes Sağıroğlu that the system had reported over 1,000 abnormal findings and physicians work closely with it because they trust it.

Replication attempts

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Later findings

The May 2023 Turkish press coverage reported the published case; no later development in the patient's treatment or the algorithm's deployment was found.

Availability

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Institutional decision

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Grounds

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Action and result

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Success criterion

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Evidence

Source numbers

AIBD-0117-source-0001–0004

Citations

Numbered references below.

Language

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Source relationships

Developer, Independent

Original evidence

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Access and versions

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Supported findings

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Evidence strength

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Missing evidence

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Grades

Assessed benefits

People.

Depth

People: 2.

Reasons

People: One identifiable patient had a diffuse glioma found during her scan, was biopsied the next day and referred for immediate oncological treatment. That was instead of the days the authors say radiology typically needs and the longer wait before treatment. The paper reports no follow-up and no changed outcome. The “saved a life” wording is Anadolu Agency's headline, not the authors' claim.

Observed or intended

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Rubric

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Assessor and date

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Alternative assessments

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Fill

Independently reported

Entry details

Kind

Not assessed

Field

Healthcare - neurosurgery / brain MRI. Hospital real-time MRI anomaly alerting (academic, non-commercial).

Purpose

The Turkish Brain Project algorithm was built to detect abnormalities on brain MRI as images are acquired and warn the responsible physicians at once. So the days the authors say radiology typically needs to report, and the longer wait before treatment, are cut to days. Anadolu Agency reports it was trained on stroke, hemorrhage and tumor cases. Flagging this patient's tumor mid-scan is that intended use.

Dates

Date basis unassessed: 2022 (precision unassessed). Updated: 22 October 2026.

Stage

Not assessed

Version

SHA-256: f2fd1ed0ddbe…

References

Other identifiers

oecd_aim: 2023-05-20-a638.

Category mappings

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Brief

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Revisions

5 revisions. Latest: 22 October 2026.

Sources

  1. Case report Developer

    Sozer A, Borcek AO, Sagiroglu S, Poshtkouh A, Demirtas Z, Karaaslan MM, Kuzucu P, Celtikci E (2023). The first case of glioma detected by an artificial intelligence algorithm running on real-time data in neurosurgery: illustrative case. Journal of Neurosurgery: Case Lessons 5(19): CASE22536, published 8 May 2023, doi:10.3171/CASE22536, PMID 37158388, PMCID PMC10550689, CC BY-NC-ND 4.0. All authors at Gazi University; their team built and deployed the algorithm, so marked as maker-authored.

  2. Case report Developer

    Sozer A et al. (2023). Journal of Neurosurgery: Case Lessons 5(19): CASE22536 (second quotation, on the operation; the case narrative dates the alert to October 2022, the biopsy to the following day, and the pathology to an isocitrate dehydrogenase wild-type diffuse glioma). Open-access copy at PubMed Central.

  3. News report Independent author

    TRT Haber, from Anadolu Agency (2023). Tıp tarihinde ilk: Yapay zeka hayat kurtardı [A first in medical history: artificial intelligence saved a life]. TRT Haber, Health, 22 May 2023, source credited as AA; quotes Assoc. Prof. Emrah Çeltikçi and Prof. Şeref Sağıroğlu of Gazi University on the 5-10 second evaluation, the phone alerts and the six-month training.

  4. News report Independent author

    Habertürk, from Anadolu Ajansı (2023). Yapay zekanın erken uyarıyla hayatını kurtardığı hasta tıp tarihine geçti [Patient whose life was saved by AI's early warning enters medical history]. Habertürk, Health, 23 May 2023, byline Anadolu Ajansı; identifies the patient as a 46-year-old woman, quotes Çeltikçi on the phone alert and Sağıroğlu on over 1,000 abnormal findings reported from the hospital's three MRI scanners and a pledge to install the system free in all public hospitals.