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They estimated that the rate of adenoma detection was 23% higher with CADe than with standard colonoscopy, at 44.3% against 37.1%. Detection of polyps and sessile serrated lesions also improved, and differences in withdrawal time were small. HTW found no evidence that CADe detected more advanced adenomas or cancers, and no trial measured cancer rates or survival over the long term. In its own economic model, HTW estimated that CADe costs an extra £4,197 for each quality-adjusted life year gained. The appraisal panel concluded that the evidence supports routine adoption, and HTW asked for data on use in practice. 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Artificial Intelligence (AI)-assisted endoscopy in the detection of gastrointestinal cancer and pre-cancerous lesions. Guidance GUI055, April 2024 (topic page, outcome of the appraisal).","title":"Artificial Intelligence (AI)-assisted endoscopy in the detection of gastrointestinal cancer and pre-cancerous lesions","url":"https://healthtechnology.wales/reports-guidance/ai-assisted-endoscopy-for-gastrointestinal-cancer/","written_by":"independent","quote":"The evidence supports the routine adoption of computer aided detection (CADe) colonoscopy for the detection of lower gastrointestinal cancer and pre-cancerous lesions. Compared with standard colonoscopy, CADe is associated with improved detection of adenomas, polyps, and sessile serrated lesions, without considerable increases to withdrawal time."},{"kind":"assessment report","citation":"Health Technology Wales. Evidence Appraisal Report EAR055: Artificial intelligence assisted endoscopy in the detection of lower gastrointestinal cancer and pre-cancerous lesions. 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It supports routine adoption.","account":"Health Technology Wales (HTW) appraised AI-assisted endoscopy for lower gastrointestinal cancer and published its guidance in April 2024. In computer-aided detection (CADe), the software draws a box around areas of concern on the live colonoscopy video, and the endoscopist decides what to remove. HTW's researchers pooled 36 randomized trials with 27,870 participants. They estimated that the rate of adenoma detection was 23% higher with CADe than with standard colonoscopy, at 44.3% against 37.1%. Detection of polyps and sessile serrated lesions also improved, and differences in withdrawal time were small. HTW found no evidence that CADe detected more advanced adenomas or cancers, and no trial measured cancer rates or survival over the long term. In its own economic model, HTW estimated that CADe costs an extra £4,197 for each quality-adjusted life year gained. The appraisal panel concluded that the evidence supports routine adoption, and HTW asked for data on use in practice. 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In computer-aided detection (CADe), the software draws a box around areas of concern on the live colonoscopy video, and the endoscopist decides what to remove. HTW's researchers pooled 36 randomized trials with 27,870 participants. They estimated that the rate of adenoma detection was 23% higher with CADe than with standard colonoscopy, at 44.3% against 37.1%. Detection of polyps and sessile serrated lesions also improved, and differences in withdrawal time were small. HTW found no evidence that CADe detected more advanced adenomas or cancers, and no trial measured cancer rates or survival over the long term. In its own economic model, HTW estimated that CADe costs an extra £4,197 for each quality-adjusted life year gained. The appraisal panel concluded that the evidence supports routine adoption, and HTW asked for data on use in practice. 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