{
  "id": "AIBD-0271",
  "title": "GPT-5 names caruncle oncocytoma from slit-lamp photos in two retrospective cases, months after histology",
  "summary": "Sassari ophthalmologists gave ChatGPT (GPT-5) slit-lamp photos and brief summaries of two surgically confirmed caruncular oncocytomas; it proposed oncocytoma first in both. Retrospective proof only.",
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  "account": "Sacchi et al. (Frontiers in Ophthalmology, 24 April 2026) retrospectively analyzed two cases of caruncular oncocytoma. Both had been excised and confirmed histopathologically. ChatGPT (GPT-5, 2025 version) received only slit-lamp photographs and a brief summary (age, sex, site). It proposed oncocytoma as the primary hypothesis in both. Differentials included papilloma, nevus, squamous cell carcinoma and melanoma. The authors call it a proof of concept that a general-purpose multimodal model can recognize a rare ocular surface tumor, limited by the sample size. The analysis was run on 8 September 2025, months after confirmation, with no effect on care. The authors declare no competing interests. Publication was 24 April 2026.",
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  "purpose": "Test whether a multimodal large language model can generate diagnostic hypotheses from slit-lamp images",
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      "depth": null,
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      "kind": "case report",
      "citation": "Sacchi M, Ellecosta C, Sechi S, Dore S, Pinna A. Front Ophthalmol 6:1772378 (2026)",
      "title": "Artificial intelligence-assisted diagnosis of ocular caruncle oncocytoma: a proof-of-concept case report of two cases",
      "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13169155/",
      "date": "2026-04-24",
      "written_by": "deployer",
      "quote": "In both cases, ChatGPT proposed oncocytoma as the primary diagnostic hypothesis."
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      "Slit-lamp photographs plus a brief clinical summary submitted to a multimodal model"
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      "Prospective testing before any clinical use",
      "Larger samples than two cases"
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    "echoes": []
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    "status": "unknown",
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      "date": "2026-10-21",
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      "date": "2026-10-21",
      "change": "Country of the deployer added from the organization's own site or a registry.",
      "source": "https://en.wikipedia.org/wiki/University_of_Sassari",
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      "date": "2026-10-21",
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      "source": "https://en.wikipedia.org/wiki/OpenAI",
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      "date": "2026-10-21",
      "change": "Prose pass: a rating reason, account, the system's part rewritten in shorter sentences with abbreviations expanded; facts, figures and quotations unchanged.",
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